Secular Trends of Incidence of Late Preterm in Korea: 1995~2012 |
박상화1, 임달오2 |
1서울대학교 의학연구원 인구의학연구소 2한국보건산업진흥원 |
우리나라 후기조기분만 발생 추이에 관한 연구: 1995~2012 |
박상화1, 임달오2 |
1서울대학교 의학연구원 인구의학연구소 2한국보건산업진흥원 |
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Abstract |
Objectives The objective of the study was to analyze the secular trend of late preterm birth(LPT: 34~36 weeks) by analyzing birth certificated data (1995: 713,038, 2000: 632,440, 2005:430,662, 2010: 468,607, 2012: 484,052) of Korea Statistics.
Methods Odds ratio and 95% confidence intervals were calculated from logistic regression analysesto describe the secular trend (1995~2012) of LPT adjusted for infantile sex, birth order,number of fetus, maternal age, maternal education & occupation, and marital status (marital &extra-marital birth).
Results The incidence of infants born LPT rose 2.6 times, from 1.9 percent to 4.9 percent, during1995~2012. The mean gestational age decreased from 39.67 weeks in 1995 to 38.63 weeks in2012. After adjustment by logistic regression for infantile sex, birth order, number of fetus,maternal age, maternal education & occupation, and marital status (marital & extra-marital birth),the odds ratio of LPT in birth year of 2000, 2005, 2010 and 2012 were, respectively, 1.57 (95%confidence interval: 1.54~1.61), 1.99 (1.94~2.04), 2.44 (2.38~2.50), and 2.52 (2.46~2.58), comparedwith incidence of LPT in 1995. Between 1995 and 2012, the rate of increase in LPT washigher in marital birth (vs. extra-marital birth), in multiple birth (vs. singleton birth), and in maternalage at <35 years (vs ≥35 years).
Conclusion The possible contributing factors to the rising LPT rate included advanced maternalage, artificial reproductive technologies, multiple births, and extra-marital birth. There was a needto more research in this area to understand the contributing risk factors for increasing LPT. |
Key Words:
late preterm birth, secular trend |
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