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J Korean Soc Matern Child Health > Volume 22(2); 2018 > Article
Journal of The Korean Society of Maternal and Child Health 2018;22(2):106-111.
DOI: https://doi.org/10.21896/jksmch.2018.22.2.106    Published online May 31, 2018.
Risk Factors for Preterm Birth in Advanced Maternal Age
Eun Jin Kwon, Kyung Ju Lee, Angela Cho, Sunwha Park, Mi Hye Park, Young Ju Kim, The Korean Preterm Collaborate Network Group
Department of Obstetrics and Gynecology and Ewha Medical Research Institute, Ewha Womans University Medical School, Seoul, Korea
고령 임산부에서 조산에 영향을 미치는 위험 요인
권은진, 이경주, 조안젤라, 박선화, 박미혜, 김영주, 국내 조산 레지스트리 그룹
이화여자대학교 의과학연구소 산부인과교실
Correspondence:  Young Ju Kim,
Email: kkyj@ewha.ac.kr
Abstract
Purpose
To identify the potential risk factors for preterm birth (PTB) in women with advanced maternal age in the Korean population.
Methods
We selected the data of 531 pregnant women and singletons in the Korean Preterm Collaborate Network Study. Among the data, we analyzed variables related to demographic characteristics, lifestyle factors, and delivery information. Maternal age was divided into two groups: younger (<35 years) and advanced (≥35 years). Multiple logistic regression analysis was performed to identify the potential risk factors for PTB in advanced maternal age.
Results
In advanced maternal age, education level, occupation, passive smoking, iron intake, and parity showed significant differences between term birth and PTB. In particular, women who were exposed to passive smoking (odds ratio [OR]=2.83, confidence interval [CI]=1.14~7.04) and had folic acid intake during pregnancy (OR=2.67, CI=1.11~6.43) were at a significantly increased risk of PTB, after adjusting for all variables.
Conclusion
This study indicates that smoking and lifestyle factors are the potential risk factors for PTB in advanced maternal age.
Key Words: Advanced maternal age, premature birth, pregnancy, smoking, lifestyle
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